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The Prostate: Part I – BNP What is situated below a body of water, has four zones and is commonly associated with venial pleasures. No it is not some romantic European city, but rather a walnut sized male organ that serves important procreative functions. It also happens to be an organ that plagues men as we age. This organ or gland is the prostate. This is the first of two articles on the male prostate. This article will focus on a disease process that affects older men, something we refer to as benign prostatic hyperplasia (BPH). BPH is a non-cancerous growth in the size of the prostate gland that impairs the flow of urine out of the bladder. The second article will focus of prostate cancer. But first a little about the small yet important male organ. The gland is located just below the bladder. It usually measures one inch by one-and-a-half inches (approximately the size of a walnut). It surrounds the urethra (the tube that takes urine out of the bladder). It is responsible for producing a fluid important in male sexual function. In the past the prostate was described as having “lobes”, but today we refer to it as having concentric zones. These zones are important both on an anatomical as well as histological level. We can separate pathology along these zones as well. For instance most all cancers occur in the peripheral zone while the benign process of enlargement occurs almost exclusively in the transitional zone (which only occupies about 5% of the total prostate volume). The prostate gland is also made up of different cell types. Cancer cells develop from the epithelial cells, but it is the interaction with stromal cells that is important in the behavior of the cancer. BPH develops from an interaction between these cells as well, but it is complex and poorly understood. Testosterone and other hormones and their interactions with this gland are hot topics of research in understanding prostate disease. The prostate gland produces most of what is found in the male ejaculate. The average volume is about 3 mL. This is less than a teaspoon and only 1% of it is sperm. The majority of the semen volume is made of products of the seminal vesicles and the prostate. The male ejaculate is very rich in potassium, zinc, citric acid and fructose. Along with these substances it also contains prostaglandins. There are many other unusual substances found in the semen. Not all is know about their function or purpose. This important male organ is a complex mix of anatomical structures and cell types that make it possible for human reproduction. However beyond the reproductive years of men, this organ becomes one of burden rather than usefulness. We will discuss the finer points of BPH and how to best avoid it and if plagued with it, treatment options. BPH typically affects men from their fourth to fifth decade of life and beyond. Several hormones come into play that have a drastic effect on the transitional zone (the zone that is most central and surrounding the urethra). Namely a metabolite of the male androgen Testosterone called Dihydrotestosterone (DHT) plays a big part on the enlargement of cells of the prostate and the encroachment on the urethra. There are several signs and symptoms that correlate with BPH and they are: slow urinary flow, the urge to urinate all the time, nighttime urination, enlargement and distension of the bladder with continuous urine leakage (incontinence) and urinary obstruction. Autopsies suggest that more than 90% of men older than 70 years have BPH. The average age for symptomatic development is about 65 years for white Americans and about 60 years for African-American men. Ways to prevent the effects of DHT on the prostate gland and the ensuing enlargement are via medications that block the enzyme 5-alpha-reductase, which converts Testosterone to DHT. Proscar is such a drug commercially available through a pharmaceutical company. Proscar works on blocking the effects of androgens on the epithelial cells and can actually shrink the size of the prostate making some of the symptoms of BPH resolve. Alternatively two FDA approved drugs that aid in symptoms of BPH (but act differently than Proscar) are Hytrin and Cardura. Both Hytrin and Cardura are drugs in the alpha1-blocker class. Originally researched as a centrally acting blood pressure reducer for patient with hypertension, it was discovered that this drug would actually relax the prostate tissue surrounding the urethra making symptoms of BPH resolve. Side effects generally include low blood pressure, dizziness, and nasal stuffiness. While neither of these two drugs will “cure” or reverse the process, they certainly do provide symptom relief for the patient plagued with BPH. Another way to treat this disease and a more natural approach is the use of herbs know for their anti-androgenic effects on the prostate. These include the well-studied Saw Palmetto herbal extract that blocks 5-alpha-reductase in the same manner as the prescription drug. Saw Palmetto taken in a standardized dose of 160mg twice daily has shown increased urine flow, with minimal side effects. Saw Palmetto is an herb indigenous to the Lowcountry of Georgia and South Carolina. Pygeum Africanum is shown to do the same yet it is not as effective and there is a fair degree of stomach symptoms. Pygeum is derived from an African evergreen tree. Stinging Nettles (Radix urticae) is another herb used widely in Europe for prostate health that has been shown to lower the residual urine volume in men with enlarged prostates. These phytotherapeutics (plant derived medicines), used and described by the Egyptians as far back as the 15 Century B.C., have a common compounds called phytosterols. The most effective phytosterol is beta sito sterol for BPH. None of the medications or herbs has been shown to prevent prostate cancer. These prescription medications and herbs are for the treatment, reduction in size or prevention of the benign process of enlargement of the prostate. Prostate cancer prevention and treatment is by other means and the subject of the next article. Besides the herbal and drug therapies there are a few surgical therapies worth mentioning. These include the most common transurethral resection of the prostate or TURP. This is where under the care of an urologist the constricted urethra within the prostate gland is “reamed out” thus mechanically or surgically widened the opening. A variant of this is the transurethral incision of the prostate (TUIP) where an incision rather than resection of the tissue is performed. A suitable procedure for patients with prostates 100 mL in volume. This involves an abdominal operation and removal of the whole prostate. Of course symptoms mentioned above for TURP are of greater frequency with this more radical procedure. There is also thermotherapy (a type of microwave treatment) that alleviates irritative symptoms, but not much is available in long-term results in the medical literature. And finally stent placement is an option. This can be used in selected cases of patients with a poor general condition and in the non-operative candidate. Symptoms of BPH include: Obstructive symptoms: Hesitancy in initiating voiding (trouble getting started) Weak urinary stream, prolonged voiding Post-voiding dribbling (mild incontinence) Sensation of incomplete emptying Nocturia (night time urination) Overflow incontinence Acute urinary retention (very painful condition) Irritative symptoms: Dysuria (discomfort in urination) Frequency Urgency Scoring BPH: The American Urological Association Symptom Index (AUASI) and International Prostate Symptom Score (IPSS) are now considered the gold standard measurement tools for the assessment of BPH symptoms and response to treatment. Both questionnaires can be used by a physician in a clinical practice to quantify the subjective symptoms of BPH and monitor therapies. Part II in this series will cover annual examination of the prostate, blood testing, prostate cancer. It will also cover prevention and treatment of prostate cancer. Reference: http://www.prostatehealth.com Lowe, FC. Et al, Phytotherapy in treatment of benign prostatic hyperplasia: a critical review. Urology 48:12-19, 1996 Dreikorn, K. et al, Stellenwert von Phytotherapeutica dei der Behandulng der benighnen Prostatahyperplasia. Urologe (A)34:119-129, 1995 Fitzpatrick, J.M. et al, Phytotherapeutic Agents in Management of Symptomatic Benign Prostatic Hyperplasia. Urological Clinics of North America. 22:407-412, 1995 Wilt T, Ishani A, Mac Donald R.. Serenoa repens for benign prostatic hyperplasia. The Cochrane Database of Systematic Reviews 2002, Issue 3. Art. No.: CD001423. DOI: 10.1002/14651858.CD001423. [Research by Sagalowski and Wilson, 1998] © 2005 vimax penis enlargement before and after photo penis enlargement surgery picture safe pennis enlargement penis enlarement pump vimax penis enlargement pills review penis enhancement information vimax penis enlargement program vimax pills

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There was a couple, Brenda and Rob, who lived in my neighborhood. They were happily married and were passionately in love even after 5 years of togetherness. Just after Christmas, on a cloudy morning I saw an ambulance taking the husband to the hospital. He suffered a heart attack. Since that day things started changing, the chemistry between the two which was an example for other couples started fading into the black darkness. This is a common scene within a couple. Mainly after a heart attack, couples are not comfortable with each other especially when it comes to having Sex. Sex is restricted for initial few months after the attack or the heart failure and later too, the wives are concerned about its adverse effects on their husband’s heart and so they start avoiding sex. Having a heart attack also brings forward certain facts; it shows that the patient has a problematic blood flow, an elevated cholesterol level and narrow blood vessels with plaque. All these facts point out to the serious possibility of having erectile dysfunction. With cardiac risks, it is not true that you need to lead a sex-less life. In fact it is safe to resume sex after a heart attack as advised by your doctor. If you are suffering from erectile dysfunction, Viagra is there to ensure strong erection. Actually, the recent studies on PDE5 inhibitors focus on their potential role to protect the heart from heart attack and reduce the chances of heart failure. Essentially, the main mechanism of Viagra or Sildenafil Citrate is relaxing the muscles to help blood flow. The erectile function mainly depends on the amount of blood that flow into the penis. The main function of the heart is to regulate the oxygen supply using blood flow to the different parts of the body. If the cardiovascular system is not smooth enough, it impedes the blood flow. The wonder drug Viagra can work on heart as well. Amazing isn’t it? Depending on the findings of the scientists from different corners of the world, I can say that Viagra can help the sexual life of a person who has recently suffered heart attack. Of course, he must take doctor’s advice and take care of other medicines he may be taking for the treatment of heart disease. So, for the sweet couples like Brenda and Rob, Viagra is there to take their care. Trust me, the chemistry between the lovers can never fade and is always there…all it requires is a small punch, which Viagra can give to your life. ___________________________________________________________________ penis enlargement exercise penile enlargment operation penile enlargement video penile enlargement program vimax penis enlargement program vimax penis enlargement technique penis enlagement product best pennis enlargement surgery vimax best penis enlargement

Many men suffer from erectile dysfunction (ED) -- the inability to achieve and sustain an erection long enough to have enjoyable and fulfilling sex. For a variety of reasons ED is most common in men over 45. The sex drive is often lowered even further in older men who are taking medications of various kinds. Most of us assume the sex drive gradually diminishes as we get older, so we are prepared to accept ED as a natural condition. But the fact is, the inability for many men to sustain an erection may be more the result of treatable physical conditions rather than an actual loss of sex drive. Until the early 1980s most people -- including most trained urologists -- assumed that ED was basically a mental or psychological problem. But in 1983 at a presentation to the American Urological Association, Dr. Giles Brindley demonstrated that a penis could be made erect by injecting it with the drug phentolamine. In a public demonstration, he used his own penis to make the point. Brindley had discovered that the penis could be made erect by relaxing the normally consricted blood vessels leading into it. Once the blood vessels are relaxed, they let in more blood and the penis inflates something like a balloon to form an erection. So gradually it came to be accepted that ED is the result of physical changes in the adult male -- not primarily mental or psychological conditions. Viagra - Controlling the Penile Valve Phentolamine -- the drug used by Dr. Brindley to give himself a public erection -- started to be used with some success in the 80's and 90's, but there are two problems with phentolamine. First, it is not selective enough to target only the penis, so its effects on other parts of the body are unpredictable. And second, the erections it creates are not brought on by sexual stimulation. You can get an erection any old time with phentolamine, and you will continue to have one until the effect of the drug wears off. Viagra was the first drug that overcame these two problems. (It was introduced in 1998 by the Pfizer company. The active ingredient in Viagra is sildenafil citrate.) Viagra does not work by relaxing the blood vessels of the penis. Instead it enhances the natural processes that take place when a man is sexually stimulated. It does this by controlling what we might call the "Softeners" -- the chemicals in the body designed to make the penis go soft after an erection. It works something like this. When a man is sexually stimulated his brain sends signals that trigger the production of chemicals that relax the blood vessels in the penis. Think of these as "Hardeners". As the blood vessels are relaxed by the production of Hardeners, blood flow increases and the penis goes erect. But nature has also designed a way for the erection to gradually subside. At the same time as Hardeners are being produced to relax the blood vessels, the body is also producing Softeners to break down and neutralize the Hardeners. These are an enzyme known as phosphodiesterase (PDE5). As long as the sexually stimulated male is producing more Hardeners than Softeners, the penis will remain erect. But as soon as the production of Hardeners starts to go down, the Softeners will get the upper hand, and the erection will start to fizzle. It is now generally assumed that ED is caused by an imbalance of Hardeners and Softeners. The body is either not producing enough Hardeners, or too many Softeners. Either way, the result is the inability to sustain an erection. What Viagra does is block the production of Softeners. This allows the Hardeners to build up in the blood vessels of the penis and create hard, sustained erections. The beauty of the process is that nothing happens without sexual stimulation. Viagra does not take the place of stimulation. Instead, it simply lets the natural chemicals created by sexual stimulation do their work. After sex, when the brain is no longer creating Hardeners, the erection subsides naturally. And when the effects of Viagra wear off -- normally after 4 or 5 hours -- the normal processes are restored to the way they were before taking the drug. Of course, as with any drug, there are potential side effects. Viagra should not be taken if you are taking any nitrate-based drug, including nitroglycerin or if you are on any blood pressure or heart medication, as combining Viagra with these drugs can cause a severe drop in blood pressure. Also, if you have any liver or kidney problems it is not recommended that you take Viagra. penis enhancement excercises vimax free natural penis enlargement easy enlargement free pnis surgery way penis enlarement drug best pnis enlargement penis enhancement herb cheap penis enlagement pro solution review vimax best penis enlargement

Erectile dysfunction can occur in various degrees. It may range from an erection not rigid enough for sexual intercourse to an erection that cannot be sustained long enough to finish a sexual act or a complete inability to achieve an erection. One should not be dogmatic in its treatment for it proves to be very fatal in breaking a relationship as well in one’s personal life. As a result of intense result on erectile dysfunction, proper and effective medicines are now readily available in the market. A new open label clinical research has shown that the oral drug Levitra is proving to be very effective in improving erectile function in most men. Studies also show that, its adverse affects are generally mild and moderate. The most common adverse effects were headache, flushing and nasal congestion. But these effects are not permanent and ceases within few hours or days. Levitra takes 30-60 mins to give an incredibly hard reaction with a naturally enhanced sex drive to finish a sexual intercourse. Its constituent Vardenafil HCL is found to be a very active substance. It increases the blood flow to the Penis and gives relaxation to the nerves in the Penis. This results in a hard and a bulging erection. Levitra provided first-time success and reliable improvement of erection quality for many men, including those with high cholesterol, high blood pressure, or diabetes. Hence FDA approved Levitra has proven effective treatment for erectile dysfunction found in men. The most commonly reported side effects are also found to be mild and moderate, and may include- headache, flushing and nasal congestion. Although, it is readily available on-line, but keep in mind that you should never do so without consulting a doctor. Levitra is really simple, effective and natural. It has definitely given manhood back. It really helps to optimize your sexual health and performance. penile enlargement tool vigrx pic result review vigrx vimax penis enlargement pills review penis enlagement traction device best elargement exercise penis penile enlargement picture penis elargement pump vimax best penis enlargement

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