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Overview Melatonin is a natural hormone, which is produced and secreted by the pineal gland. Melatonin plays an important role in the regulation of many hormones in the body. Among its key roles, melatonin controls the body's circadian rhythm, an internal 24-hour time-keeping system that controls when we fall asleep and when we wake up. Melatonin is also a very powerful antioxidant. In one study, melatonin was 60 times more effective than Vitamin C or water-soluble Vitamin E in protecting DNA from damage. Preliminary evidence suggests that it may help strengthen the immune system. There are numerous claims and theories concerning all the things that melatonin may do and as a result it has become one of the popular life extension and life enhancing supplements that are currently available on the market today. Uses The most accepted function of Melatonin is it role in sleep regulation. Melatonin supplements help induce sleep in people with disrupted circadian rhythms. Melatonin is significantly more effective in decreasing the amount of time required to fall asleep, increasing the number of sleeping hours, and boosting daytime alertness. Melatonin is purported to be one of those miracle substances that has a hand in everything. This may be due to the fact that during the height of the antioxidant craze, Melatonin was found to be a more powerful and more universal antioxidant than both vitamin C and vitamin E. Whatever the reason, Melatonin ostensibly plays a role in numerous health conditions. Here is a partial list: Insomnia Osteoporosis Menopause Depression Eating Disorders Breast Cancer Prostate Cancer Cancer-related Weight Loss Sarcoidosis Rheumatoid Arthritis Epilepsy Sunburn Viral Encephalitis Heart Disease Since a lot of evidence for many of these claims is rather light and since I am not trying to sell you melatonin supplements, I am going to focus only on its role in sleep enhancement. Insomnia As many parents realize, drugs like Ritalin are not without side effects. One of the major complaints that parents have is that their children who take Ritalin can't fall asleep at night. Many parents report that their children, who may be only five or six years old, are wide awake until 11 pm or later. Melatonin may be able to help these children. Since it is the primary chemical in the body that helps to induce sleep, children who suffer from insomnia often find that Melatonin restores their normal sleep cycle and helps them to be more awake and alert during the day. How to Take It There are currently no guidelines as to how to take Melatonin. Sensitivity to Melatonin is an individual thing and doses that are ineffective in one person may be too much for someone else. The best approach for any condition is to begin with very low doses and slowly add more until you get the effect that you are seeking. In children, it is best to start with a dose of about 0.3 mg/day or less. Although current research suggests that even doses as high as 10 mg are perfectly safe, it is best to proceed with caution. In adults, 3 mg is usually a safe starting dose and you can increase it or decrease it as you see fit. Availability Melatonin is readily available in most health food stores in the United States and it is very cheap. In Europe it is a controlled substance. Most Europeans who wish to use Melatonin find it cheaper and easier to have it shipped from the US. Adverse Effects Melatonin is one of the least toxic substances known. In one extensive clinical trial, a high dose of 75 milligrams of melatonin per day was given to 1400 women in the Netherlands for up to four years with no ill effects. The only consistent side effect of high doses has been drowsiness and a slower reaction time. Other common complaints include: Vivid dreams or nightmares Stomach cramps Dizziness Headache Irritability Decreased libido Breast enlargement in men Decreased sperm count These side effects were in healthy people. We also don't know how melatonin may affect people suffering from disease. Possible Drug Interactions Melatonin may interact or interfere with other drugs. These include: Antidepressant Medications Antipsychotic Medications: many of these medications are now being used in treating children with ADHD and Bipolar disorder Benzodiazepines Blood Pressure Medications Blood-thinning Medications, Anticoagulants Interleukin-2 Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Steroids and Immunosuppressant Medications Tamoxifen If your child is taking any of these things, you should consult with his doctor before giving Melatonin. Also, caffeine, tobacco, and alcohol can all diminish levels of melatonin in the body while cocaine and amphetamines may increase melatonin production. Conclusion Often children with ADHD have a great deal of difficulty falling asleep. This can be due to the medications that they are taking or just be one component in the spectrum of their problems. When used properly, melatonin may be a safe and effective way to handle sleep problems in ADHD children. Anthony Kane, MD ADD ADHD Advances http://addadhdadvances.com Attention Publishers: This article is available for your website or ezine. For an ezine, send an email to: melatonin@addadhdadvances.com. For a website send an email to: melatoninhtml@addadhdadvances.com herbal natural penis enlargement erection penis pills size vimax vimax penis enlargement traction device natural penile enlargement pills penis enlargment pills review penis enargement forum buy penis enlagement pills do penis enlagement pills work
The Arabic Jelqing (or Arabic Jelq) is a very old arabian technique. The name Arabic Jelq originated in the Middle East where fathers used to prepare their sons for sexual relationships by showing them a penile massage technique (jelqing) which enlarged the size of the penis. The aim of Arabic Jelq is to enlarge the penis by increasing the blood pressure in the penis, with the purpose of permanently growing the maximum erect size of the penis itself. Arabic Jelq, also known as "milking", consists of wrapping the thumb and index finger around the base of penis while semi-erect and repetitively forcing them to force blood into the glands, encouraging in this way more vascularity in the corpus cavernosa and related tissues. Arabic Jelq is considered one of the best and more effective penis enlargement exercise and actually it’s the most practiced penis enlargement method in USA. In the late 70’s Dr Brian Richards, carried a very comprehensive research about the effectiveness of the Arabic Jelq and his research was published also by the British Journal of Sexual Medicine and showed extremely positive results for 87% of the test group. He demonstrated Arabic Jelq increased the penis length of up to 1.4 inches and the penis girth of up to 1 inch. There are a lot of products related to Arabic Jelq available on the penis enlargement market; anyway, you can find much of what they offer (instructions) on forums and websites for free. Before beginning a penis enlargement routine, you should contact somebody competent with the Arabic Jelq. Arabic Jelqing is usually preceded by a warm up with a warm towel on the genitals, and with a warm down done in the same way. free penile enlargment video penile enlargement picture vimax penis enlargement program pnis enlargement magna rx pill penis elargement tip best enlargement exercise penile penile enlargement traction device penis enlargment surgeries
Who would have thought 8 years back that sildenafil citrate, a drug used for the treatment of angina pectoris (a cardiovascular disease), could work wonders for treating male erectile dysfunction (ED)? The results were astounding. The drug was less effective for angina but provided astonishing results in treating ED. It was patented in 1996 by the drug company Pfizer and approved for use in ED by the FDA on March 27, 1998. No other drug was approved before in the US to treat ED. Pfizer used brand name ‘Viagra’ for its hitherto new product. The name rhymes with the famous “Niagra” falls (ostensibly evokes a sense of incredible erectile and ejaculatory strength). Another theory has it that ‘Viagra’ originates from the Sanskrit word “vya-ghra", which means tiger. Viagra is also informally known as "Vitamin V", "the Blue Pill", “the Wonder Pill” and various other nicknames. It is a prescription drug and must be taken after thorough consultation with the doctor. The reasons for the popularity of Viagra are obvious. According to a study, there are estimated 30 million clinically impotent men in the US. The causes for such impotence may be psychological, resulting from stress, fatigue, anxiety, or depression. But over 90% of the time, there are identifiable biological problems. The ED or impotence is prominent amongst men over 50 due to various hormonal changes in the body. This could result in partial or total loss of sexual function. It is here that Viagra scores over the traditional treatment options like penile implants, injectable drugs (into the penis), and vacuum constriction devices. Viagra Mechanism? Simply, Viagra keeps the smooth muscle of penis relaxed. A relaxed penis allows good blood flow in and generation of an erection. Viagra works in sync with the natural processes of the body. It blocks the action of type 5 phosphodiesterase enzyme (PDE5). This enzyme, in turn, promotes the accumulation of cyclic guanosine monophosphate (cGMP), a compound that causes a reduction in the amount of calcium within a muscle cell. This, in turn, results in relaxation of that muscle cell and promotes penile erection. The more cGMP inside the cell, the better the erection will be. However, cGMP is broken down by the PDE5 enzyme, which is available in large supply in the penis. This is why Viagra's ability to block the action of PDE5 is so essential. The drug allows the accumulation of cGMP, which permits an erection to develop and be maintained. Side Effects The likelihood of side effects increase as the dosage gets stronger. Some of the known side effects of Viagra are – Severe headache Dizziness or loss of balance Nasal problems Abnormal vision Indigestion Complete blackouts Severe hypotension (low blood pressure) Sudden death in extreme causes Overall, despite the obvious risks, Viagra is an incredible positive development for men suffering from erectile dysfunction. Other Benefits Recent research has found that Viagra can reduce the effects of stress on the heart. Scotland on Sunday has recently reported that consultants at York hill Children's Hospital in Glasgow are using Viagra as a life-saving treatment for children suffering from pulmonary hypertension, a cause of so-called "blue baby" syndrome that affects the blood flow to the lungs. prosolution penis enhancement pills penile enlargement pills discount vig rx free penis enlarement pills penis enlarement information surgical penile enlargment vimax penis enlargement information do penis enlagement pills work penis enlargment surgeries
The Prostate: Part I – BNP What is situated below a body of water, has four zones and is commonly associated with venial pleasures. No it is not some romantic European city, but rather a walnut sized male organ that serves important procreative functions. It also happens to be an organ that plagues men as we age. This organ or gland is the prostate. This is the first of two articles on the male prostate. This article will focus on a disease process that affects older men, something we refer to as benign prostatic hyperplasia (BPH). BPH is a non-cancerous growth in the size of the prostate gland that impairs the flow of urine out of the bladder. The second article will focus of prostate cancer. But first a little about the small yet important male organ. The gland is located just below the bladder. It usually measures one inch by one-and-a-half inches (approximately the size of a walnut). It surrounds the urethra (the tube that takes urine out of the bladder). It is responsible for producing a fluid important in male sexual function. In the past the prostate was described as having “lobes”, but today we refer to it as having concentric zones. These zones are important both on an anatomical as well as histological level. We can separate pathology along these zones as well. For instance most all cancers occur in the peripheral zone while the benign process of enlargement occurs almost exclusively in the transitional zone (which only occupies about 5% of the total prostate volume). The prostate gland is also made up of different cell types. Cancer cells develop from the epithelial cells, but it is the interaction with stromal cells that is important in the behavior of the cancer. BPH develops from an interaction between these cells as well, but it is complex and poorly understood. Testosterone and other hormones and their interactions with this gland are hot topics of research in understanding prostate disease. The prostate gland produces most of what is found in the male ejaculate. The average volume is about 3 mL. This is less than a teaspoon and only 1% of it is sperm. The majority of the semen volume is made of products of the seminal vesicles and the prostate. The male ejaculate is very rich in potassium, zinc, citric acid and fructose. Along with these substances it also contains prostaglandins. There are many other unusual substances found in the semen. Not all is know about their function or purpose. This important male organ is a complex mix of anatomical structures and cell types that make it possible for human reproduction. However beyond the reproductive years of men, this organ becomes one of burden rather than usefulness. We will discuss the finer points of BPH and how to best avoid it and if plagued with it, treatment options. BPH typically affects men from their fourth to fifth decade of life and beyond. Several hormones come into play that have a drastic effect on the transitional zone (the zone that is most central and surrounding the urethra). Namely a metabolite of the male androgen Testosterone called Dihydrotestosterone (DHT) plays a big part on the enlargement of cells of the prostate and the encroachment on the urethra. There are several signs and symptoms that correlate with BPH and they are: slow urinary flow, the urge to urinate all the time, nighttime urination, enlargement and distension of the bladder with continuous urine leakage (incontinence) and urinary obstruction. Autopsies suggest that more than 90% of men older than 70 years have BPH. The average age for symptomatic development is about 65 years for white Americans and about 60 years for African-American men. Ways to prevent the effects of DHT on the prostate gland and the ensuing enlargement are via medications that block the enzyme 5-alpha-reductase, which converts Testosterone to DHT. Proscar is such a drug commercially available through a pharmaceutical company. Proscar works on blocking the effects of androgens on the epithelial cells and can actually shrink the size of the prostate making some of the symptoms of BPH resolve. Alternatively two FDA approved drugs that aid in symptoms of BPH (but act differently than Proscar) are Hytrin and Cardura. Both Hytrin and Cardura are drugs in the alpha1-blocker class. Originally researched as a centrally acting blood pressure reducer for patient with hypertension, it was discovered that this drug would actually relax the prostate tissue surrounding the urethra making symptoms of BPH resolve. Side effects generally include low blood pressure, dizziness, and nasal stuffiness. While neither of these two drugs will “cure” or reverse the process, they certainly do provide symptom relief for the patient plagued with BPH. Another way to treat this disease and a more natural approach is the use of herbs know for their anti-androgenic effects on the prostate. These include the well-studied Saw Palmetto herbal extract that blocks 5-alpha-reductase in the same manner as the prescription drug. Saw Palmetto taken in a standardized dose of 160mg twice daily has shown increased urine flow, with minimal side effects. Saw Palmetto is an herb indigenous to the Lowcountry of Georgia and South Carolina. Pygeum Africanum is shown to do the same yet it is not as effective and there is a fair degree of stomach symptoms. Pygeum is derived from an African evergreen tree. Stinging Nettles (Radix urticae) is another herb used widely in Europe for prostate health that has been shown to lower the residual urine volume in men with enlarged prostates. These phytotherapeutics (plant derived medicines), used and described by the Egyptians as far back as the 15 Century B.C., have a common compounds called phytosterols. The most effective phytosterol is beta sito sterol for BPH. None of the medications or herbs has been shown to prevent prostate cancer. These prescription medications and herbs are for the treatment, reduction in size or prevention of the benign process of enlargement of the prostate. Prostate cancer prevention and treatment is by other means and the subject of the next article. Besides the herbal and drug therapies there are a few surgical therapies worth mentioning. These include the most common transurethral resection of the prostate or TURP. This is where under the care of an urologist the constricted urethra within the prostate gland is “reamed out” thus mechanically or surgically widened the opening. A variant of this is the transurethral incision of the prostate (TUIP) where an incision rather than resection of the tissue is performed. A suitable procedure for patients with prostates 100 mL in volume. This involves an abdominal operation and removal of the whole prostate. Of course symptoms mentioned above for TURP are of greater frequency with this more radical procedure. There is also thermotherapy (a type of microwave treatment) that alleviates irritative symptoms, but not much is available in long-term results in the medical literature. And finally stent placement is an option. This can be used in selected cases of patients with a poor general condition and in the non-operative candidate. Symptoms of BPH include: Obstructive symptoms: Hesitancy in initiating voiding (trouble getting started) Weak urinary stream, prolonged voiding Post-voiding dribbling (mild incontinence) Sensation of incomplete emptying Nocturia (night time urination) Overflow incontinence Acute urinary retention (very painful condition) Irritative symptoms: Dysuria (discomfort in urination) Frequency Urgency Scoring BPH: The American Urological Association Symptom Index (AUASI) and International Prostate Symptom Score (IPSS) are now considered the gold standard measurement tools for the assessment of BPH symptoms and response to treatment. Both questionnaires can be used by a physician in a clinical practice to quantify the subjective symptoms of BPH and monitor therapies. Part II in this series will cover annual examination of the prostate, blood testing, prostate cancer. It will also cover prevention and treatment of prostate cancer. Reference: http://www.prostatehealth.com Lowe, FC. Et al, Phytotherapy in treatment of benign prostatic hyperplasia: a critical review. Urology 48:12-19, 1996 Dreikorn, K. et al, Stellenwert von Phytotherapeutica dei der Behandulng der benighnen Prostatahyperplasia. Urologe (A)34:119-129, 1995 Fitzpatrick, J.M. et al, Phytotherapeutic Agents in Management of Symptomatic Benign Prostatic Hyperplasia. Urological Clinics of North America. 22:407-412, 1995 Wilt T, Ishani A, Mac Donald R.. Serenoa repens for benign prostatic hyperplasia. The Cochrane Database of Systematic Reviews 2002, Issue 3. Art. No.: CD001423. DOI: 10.1002/14651858.CD001423. [Research by Sagalowski and Wilson, 1998] © 2005 vimax results male penis enlagement enlargment free penis pills sample best penis enlargment pills does penis elargement work enlargement erection penis pills vimax safe pnis enlargement penis enlargement surgery picture penis enlargment surgeries
Hypertension can wreak havoc on many body organs. Its effects on the heart are especially damaging. High blood pressure and heart disease are closely connected. Moderate to high blood pressure significantly increases the load on the left side of the heart. Arterioles are often diseased or constricted, which increases resistance to blood flow. When this happens, the heart has to work much more to pump blood into the arterial system including the aorta. When any muscle is overused, it tends to increase in size and bulk. The heart muscles react the same way. An enlarged heart is a sign of trouble. Heart enlargement can be detected in several ways. A chest x-ray can reveal it. So can an electrocardiogram or even a physical examination. In many high blood pressure patients, the walls of the left ventricle thicken. This increases the workload on the heart. Eventually, the heart falters and the left side of the heart no longer pumps blood adequately. When this happens, major organs and tissues of the body are denied sufficient blood supply. The affected person becomes lethargic and weak. Because of the higher pressure in the left ventricle, blood from the lungs cannot drain into the top compartment of the heart (the atrium). As a result, the lung tissues get congested which brings on bouts of breathlessness and coughs. The patient may have a dry cough or even frothy phlegm with blood stains in it. This is a very scary experience to the sufferer and onlookers. In an acute attack, it seems to the patient that he or she is choking to death. Breathlessness due to heart problems may be first noticed during prolonged physical exertion. If the condition has progressed further, breathlessness may occur even while resting. This is a serious situation and needs to be tacked immediately. If this damage worsens, the right side of the heart will be affected as well. When pressure builds up in the right atrium, it will be difficult for veins to drain blood into it. When the heart's condition deteriorates to this stage, the external jugular veins may become enlarged and more prominent. These veins are anyway close to the skin and may be visible even in healthy adults, but stress on the heart can increase their protrusion. There are several other symptoms of right side heart failure. They include an enlarged liver, swollen ankles and feet, loss of appetite, swollen abdomen and lower urine flow. High blood pressure and heart disease frequently have a cause and effect relationship. Making necessary lifestyle changes can help combat both.